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WHO: No proven link between paracetamol use in pregnancy and autism

September 24, 2025

GENEVA — The World Health Organization (WHO) stressed on Wednesday that there is no conclusive scientific evidence confirming a link between autism and the use of acetaminophen (paracetamol) during pregnancy.

Globally, nearly 62 million people — about one in every 127 — live with autism spectrum disorder, a diverse group of brain development conditions.

While awareness and diagnoses have improved in recent years, the precise causes of autism remain unclear, with multiple contributing factors believed to be involved.



WHO noted that large-scale studies conducted over the past decade have investigated potential links between acetaminophen use during pregnancy and autism, but no consistent association has been established.

The agency advised women to continue following the guidance of their doctors or health workers regarding medication during pregnancy, particularly in the first trimester.

The organization also reaffirmed that vaccines do not cause autism.

“Since 1999, independent experts advising WHO have repeatedly confirmed that vaccines — including those with thiomersal or aluminum — do not cause autism or other developmental disorders,” the agency said, citing extensive global research.

Childhood vaccine schedules, WHO added, are carefully designed by global experts and national health authorities to provide the best protection at the right time. These schedules, which now protect against 30 infectious diseases, have saved at least 154 million lives worldwide over the past 50 years.

WHO warned that delaying or altering immunization schedules without scientific evidence sharply increases the risk of infections, endangering not only children but also vulnerable groups such as infants and those with weakened immune systems.

Autism and other neurodevelopmental disorders will be among the topics discussed at the 4th UN High-Level Meeting on Noncommunicable Diseases and Mental Health on Thursday.

WHO said it is committed to improving understanding of autism and supporting autistic individuals and their families, working with autistic-led organizations and partners worldwide. — Agencies


September 24, 2025
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